Synthesis of benzothiazonine by rhodium-catalyzed denitrogenative transannulation of 1-sulfonyl-1,2,3-triazole and thiochromone
Saygbechi T. Jablasone, Zihang Ye, Shengguo Duan, Ze‐Feng Xu, Chuan‐Ying Li
Abstract
A facile synthesis of multi-functionalized benzothiazonine was achieved by the rhodium-catalyzed denitrogenative annulation of 1-sulfonyl-1,2,3-triazole and thiochromone. In view of the excellent atom economy, broad substrate scope and easy availability of starting materials, the protocol provided an efficient strategy for the construction of medium N,S-heterocycles.
Topics & Concepts
AnnulationRhodiumSulfonylChemistryCatalysisCombinatorial chemistrySubstrate (aquarium)TriazoleScope (computer science)Organic chemistryComputer scienceOceanographyGeologyProgramming languageAlkylCyclopropane Reaction MechanismsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods