Pretreatment of hydroethanolic extract of Dillenia indica L. attenuates oleic acid induced NAFLD in HepG2 cells via modulating SIRT-1/p-LKB-1/AMPK, HMGCR & PPAR-α signaling pathways

M. Poornima, Ganapathy Sindhu, Billu Abraham, C. R. Sruthi, P. Nisha, Pinku Gogoi, Gakul Baishya, K. Raghu

2022Journal of Ethnopharmacology38 citationsDOI

Topics & Concepts

LipogenesisTraditional medicineMedicineOleic acidBiologyPharmacologyBiochemistryLipid metabolismLiver Disease Diagnosis and TreatmentDrug-Induced Hepatotoxicity and ProtectionCholesterol and Lipid Metabolism

Pretreatment of hydroethanolic extract of Dillenia indica L. attenuates oleic acid induced NAFLD in HepG2 cells via modulating SIRT-1/p-LKB-1/AMPK, HMGCR &amp; PPAR-α signaling pathways

Topics & Concepts

Pretreatment of hydroethanolic extract of Dillenia indica L. attenuates oleic acid induced NAFLD in HepG2 cells via modulating SIRT-1/p-LKB-1/AMPK, HMGCR & PPAR-α signaling pathways