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Diagnostic accuracy of the ultrasensitive S-PLEX SARS-CoV-2 N electrochemiluminescence immunoassay

Giuseppe Lippi, Brandon Michael Henry, Martina Montagnana, Mario Plebani

2022Clinical Chemistry and Laboratory Medicine (CCLM)13 citationsDOIOpen Access PDF

Abstract

To the Editor, We read with interest the recent article of Ren et al. This method has been specifically developed for detecting and quantifying the SARS-CoV-2 N antigen in a variety of human specimens, including serum, plasma, saliva and nasopharyngeal swabs (NPS). Briefly, either S-PLEX 96-Well SECTOR or QuickPlex plates coated with streptavidin for binding biotin-conjugated capture anti-SARS-CoV-2 N antibodies

Topics & Concepts

ElectrochemiluminescenceImmunoassaySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Medicine2019-20 coronavirus outbreakVirologyChromatographyInternal medicineChemistryImmunologyAntibodyDetection limitOutbreakDiseaseInfectious disease (medical specialty)Advanced biosensing and bioanalysis techniquesBiosensors and Analytical DetectionSARS-CoV-2 detection and testing
Diagnostic accuracy of the ultrasensitive S-PLEX SARS-CoV-2 N electrochemiluminescence immunoassay | Litcius