Solid-phase fluorescent BODIPY–peptide synthesis <i>via in situ</i> dipyrrin construction
Yue Wu, Wing‐Sze Tam, Hoa K. Chau, Simranjeet Kaur, Waygen Thor, Wei Shen Aik, Wai‐Lun Chan, Markus Zweckstetter, Ka‐Leung Wong
Abstract
, responsive fluorescence enhancement, and higher light cytotoxicity due to the photo-generation of cytotoxic singlet oxygen. This work offers a novel practical synthetic platform for fluorescent peptides for multifaceted biomedical applications.
Topics & Concepts
BODIPYFluorescenceIn situPeptideChemistryPeptide synthesisCombinatorial chemistrySolid-phase synthesisPhase (matter)NanotechnologyBiochemistryMaterials scienceOrganic chemistryPhysicsQuantum mechanicsLuminescence and Fluorescent MaterialsSupramolecular Self-Assembly in MaterialsPorphyrin and Phthalocyanine Chemistry