A Retrospective Observational Study of the Association Between Plasma Levels of Interleukin 8 in 42 Patients with Sepsis-Induced Myocardial Dysfunction at a Single Center Between 2017 and 2020
XiaoYing Chen, Xian Liu, RuiAn Dong, Dan Zhang, Shu Qin
Abstract
BACKGROUND This retrospective, observational study from a single center aimed to evaluate the association between complement (C)3 and C4, lymphocytes markers CD4 and CD8, and the interleukins IL-1ß, IL-2R, IL-6, IL-10, and IL-8 in patients with sepsis-induced myocardial dysfunction (SIMD) and a reduced left ventricular ejection fraction (LVEF) of < 50%. MATERIAL AND METHODS Patients with sepsis from July 2017 to December 2020 were divided into a SIMD group (42 patients) and NO-SIMD group (214 patients). Diagnostic criteria of sepsis were based on SEPSIS 3.0 guidelines. SIMD was defined as LVEF.
Topics & Concepts
Single CenterMedicineSepsisInternal medicineObservational studyCardiologyEjection fractionRetrospective cohort studyGastroenterologyInterleukin 8InterleukinInterleukin 6Plasma levelsComplement (music)Group BCase-control studySepsis Diagnosis and TreatmentImmune Response and InflammationCardiac Fibrosis and Remodeling