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A systematic and robust assessment of hot-melt extrusion-based amorphous solid dispersions: Theoretical prediction to practical implementation

Abdullah Alzahrani, Dinesh Nyavanandi, Preethi Mandati, Ahmed Adel Ali Youssef, Sagar Narala, Suresh Bandari, Michael A. Repka

2022International Journal of Pharmaceutics68 citationsDOI

Topics & Concepts

ExtrusionSolubilityAmorphous solidMiscibilityMaterials scienceCompatibility (geochemistry)PolymerDosage formProcess engineeringHildebrand solubility parameterNanotechnologyBiochemical engineeringComputer scienceChemistryOrganic chemistryComposite materialChromatographyEngineeringDrug Solubulity and Delivery SystemsProtein purification and stabilityAnalytical Chemistry and Chromatography
A systematic and robust assessment of hot-melt extrusion-based amorphous solid dispersions: Theoretical prediction to practical implementation | Litcius