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Design, synthesis and Molecular modeling study of certain EGFR inhibitors with a quinazolinone scaffold as anti-hepatocellular carcinoma and Radio-sensitizers

Walid M. Ghorab, Samiha A. El‐Sebaey, Mostafa M. Ghorab

2022Bioorganic Chemistry24 citationsDOI

Topics & Concepts

ChemistryQuinazolinoneIC50Hepatocellular carcinomaAcetamidePharmacologyCytotoxic T cellErlotinibDocking (animal)EGFR inhibitorsStereochemistryCombinatorial chemistryIn vitroCancer researchBiochemistryEpidermal growth factor receptorReceptorOrganic chemistryBiologyMedicineNursingQuinazolinone synthesis and applicationsCancer therapeutics and mechanismsSynthesis and biological activity
Design, synthesis and Molecular modeling study of certain EGFR inhibitors with a quinazolinone scaffold as anti-hepatocellular carcinoma and Radio-sensitizers | Litcius