E Se tea alleviates acetaminophen-induced liver injury by activating the Nrf2 signaling pathway
Jinke Zhang, Mengcheng Li, Tianrui Zhao, Jianxin Cao, Yaping Liu, Yongpeng Wang, Yongpeng Wang, Yifen Wang, Yifen Wang, Guiguang Cheng
Abstract
Phlorizin and phloretin are the major chemical components of E Se tea. E Se tea extract promoted the expression of Keap1, Nrf2, NQO1 and HO-1 proteins in the liver tissues. E Se tea extract inhibited APAP-induced acute liver injury.
Topics & Concepts
PhlorizinAcetaminophenPhloretinLiver injuryKEAP1ChemistryPharmacologyBiochemistryTraditional medicineMedicineGeneInternal medicineTranscription factorInsulinGlucose transporterDrug-Induced Hepatotoxicity and ProtectionChemotherapy-induced organ toxicity mitigationGenomics, phytochemicals, and oxidative stress