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THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells

Chuang Sun, Peishun Shou, Hongwei Du, Koichi Hirabayashi, Yu‐Hui Chen, Laura E. Herring, Sarah Ahn, Yang Xu, Kyogo Suzuki, Guangming Li, Ourania Tsahouridis, Lishan Su, Barbara Savoldo, Gianpietro Dotti

2020Cancer Cell153 citationsDOIOpen Access PDF

Topics & Concepts

CD28Immunological synapseChimeric antigen receptorPriming (agriculture)Cell biologyT cellJurkat cellsAntigenBiologyReceptorT-cell receptorCancer researchImmunologyImmune systemBiochemistryGerminationBotanyCAR-T cell therapy researchNanowire Synthesis and ApplicationsSilicon Carbide Semiconductor Technologies
THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells | Litcius