New benzimidazole based hybrids: Synthesis, molecular modeling study and anticancer evaluation as TopoII inhibitors
Nareman A. Nawareg, Amany S. Mostafa, Shahenda M. El‐Messery, Magda N.A. Nasr
Topics & Concepts
HeLaChemistryBenzimidazoleApoptosisStaurosporineIC50Docking (animal)Cell cycleIn vitroCell cycle checkpointCancer cellCell cultureBiochemistryStereochemistryEnzymeCancerBiologyProtein kinase AOrganic chemistryGeneticsNursingMedicineCancer therapeutics and mechanismsBioactive Compounds and Antitumor AgentsSynthesis and biological activity