Assessment of Tau Tangles and Amyloid-β Plaques Among Super Agers Using PET Imaging
Merle C. Hoenig, Niclas Willscheid, Gérard N. Bischof, Thilo van Eimeren, Alexander Drzezga, Alzheimer’s Disease Neuroimaging Initiative
Abstract
This cross-sectional study examines positron emission tomography (PET) imaging to investigate the burden of tau tangles and amyloid β plaques in super agers, normal agers, and patients with mild cognitive impairment vs younger amyloid-negative controls.
Topics & Concepts
Positron emission tomographyPet imagingAmyloid (mycology)β amyloidMedicineCognitive impairmentPathologyPsychologyNuclear medicineAlzheimer's diseaseDiseaseDementia and Cognitive Impairment ResearchAlzheimer's disease research and treatmentsFunctional Brain Connectivity Studies