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Antibiotic-resistant Escherichia coli isolated from dairy cows and their surrounding environment on a livestock farm practicing prudent antimicrobial use

Yoshihiro Suzuki, Hayate Hiroki, Hui Xie, Masateru Nishiyama, Shinsuke H. Sakamoto, Ryoko Uemura, Kei Nukazawa, Yoshitoshi Ogura, Toru Watanabe, Ikuo Kobayashi

2022International Journal of Hygiene and Environmental Health20 citationsDOIOpen Access PDF

Abstract

On a livestock farm where antimicrobial administration and its history had been managed for prudent use of antimicrobials, we surveyed antibiotic-resistant Escherichia coli strains isolated from cow feces and the surrounding environment (i.e., rat and crow feces, and water samples from a drainage pit and wastewater processing tank) every month for 1 year. Two strains (1.7%) in cow feces were resistant to tetracycline, whereas all other strains were susceptible to all other antimicrobials. Among 136 strains isolated from cows and wild animals, only one ampicillin-resistant strain was identified. The antibiotic resistance rate in the drainage from the barn was 8.3% (10/120), and all strains showed susceptibility for 8 months of the year. Tetracycline resistance was common in all resistant strains isolated from animal feces and water samples; all tetracycline-resistant strains carried tetA. These results strongly support the proper use and management of antibiotics on farms to minimize the outbreak and spread of antibiotic-resistant bacteria.

Topics & Concepts

TetracyclineFecesAntibiotic resistanceAmpicillinAntibioticsAntimicrobialLivestockMicrobiologyBiologyEscherichia coliVeterinary medicineMedicineEcologyGeneBiochemistryPharmaceutical and Antibiotic Environmental ImpactsAntibiotic Resistance in BacteriaEnterobacteriaceae and Cronobacter Research