CircMAPK1 promoted CD8 + T cell infiltration in LUAD by improving the IGF2BP1 dependent CCL5 upregulation
Feng Zhao, Guorong Zhu, Jing He, Xiang Xu, Weidong Zhu, Wei Jiang, Guangming He, Guangming He
Topics & Concepts
CCL5Cancer researchChemokineTumor microenvironmentCD8Cytotoxic T cellImmune systemImmunotherapyBiologyAdenocarcinomaInfiltration (HVAC)Downregulation and upregulationCell biologyT cellMolecular biologyChemistryIn vitroImmunologyIL-2 receptorCancerGeneBiochemistryPhysicsGeneticsThermodynamicsCircular RNAs in diseasesMicroRNA in disease regulationCancer-related molecular mechanisms research