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Biotinylated platinum(<scp>ii</scp>) metallacage towards targeted cancer theranostics

Xingchen Wang, Qi Su, Zeyuan Zhang, Jin Yang, Yanmin Zhang, Mingming Zhang

2020Chemical Communications33 citationsDOI

Abstract

A biotinylated metallacage was prepared via metal-coordination-driven self-assembly, combining fluorescence, anti-cancer and targeted properties into a single entity. The metallacage was successfully employed for targeted cell imaging and therapy, offering a platform for cancer theranostics.

Topics & Concepts

BiotinylationPlatinumChemistryCancerCombinatorial chemistryNanotechnologyMaterials scienceBiochemistryMedicineInternal medicineCatalysisNanoplatforms for cancer theranosticsSupramolecular Chemistry and ComplexesLuminescence and Fluorescent Materials
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