Discovery of novel indole derivatives that inhibit NEDDylation and MAPK pathways against gastric cancer MGC803 cells
Dong‐Jun Fu, Xinxin Cui, Ting Zhu, Yanbing Zhang, Yangyang Hu, Lirong Zhang, Shenghui Wang, Sai‐Yang Zhang
Topics & Concepts
ChemistryIndole testCancer cellNeddylationApoptosisAcetamideMAPK/ERK pathwayCancerCell cycleCell cultureStereochemistryInhibitory postsynaptic potentialBiochemistrySignal transductionBiologyGeneUbiquitinGeneticsOrganic chemistryUbiquitin ligaseNeuroscienceUbiquitin and proteasome pathwaysClick Chemistry and ApplicationsCancer Mechanisms and Therapy