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Monitoring and Evaluation of Corrosion at the Interface of Zirconium Alloy Biomaterials Under Simulated Oxidative Biological Environment

Lidia Benea, Veaceslav Neaga, Nicoleta Bogatu, Elena Roxana Axente

2025International Journal of Molecular Sciences5 citationsDOIOpen Access PDF

Abstract

The present work investigates the electrochemical behavior of the Zr2.5Nb alloy in a biomedical context, emphasizing the influence of electrochemical oxidation treatment on its stability in simulated physiological environments. The alloy samples were oxidized in 1 M H2SO4 under controlled voltages (200–275 V) and times (1 min), identifying 200 V–1 min as the optimal condition for obtaining a uniform porous oxide layer with an average pore diameter of ~90 nm. The corrosion resistance was evaluated using open circuit potential (OCP) and electrochemical impedance spectroscopy (EIS) in Ringer’s solution and Ringer’s solution containing 40 g/L H2O2 to simulate physiological and inflammatory conditions. Electrochemical tests revealed that electrochemically oxidized samples exhibited a polarization resistance up to 14.78 MΩ·cm2, about 26 times higher than that of the untreated alloy (0.56 MΩ·cm2). After 77 h of immersion, the oxidized alloy maintained a high resistance (17.54 MΩ·cm2), confirming long-term stability. Scanning Electron Microscopy (SEM–EDX) and X-Ray Diffraction (XRD) analyses highlighted significant increases in oxygen content and the transformation from the monoclinic baddeleyite to the cubic arkelite phase of ZrO2, contributing to enhanced corrosion resistance. These findings demonstrate that controlled electrochemical oxidation significantly improves the durability of Zr2.5Nb alloy in oxidative environments, supporting its potential for long-term biomedical implant applications.

Topics & Concepts

Materials scienceCorrosionAlloyDielectric spectroscopyElectrochemistryScanning electron microscopeChemical engineeringPolarization (electrochemistry)OxideMetallurgyElectrolyteMonoclinic crystal systemPhase (matter)PorosityZirconiumScanning electrochemical microscopyOpen-circuit voltageTitanium alloyAnodizingEnergy-dispersive X-ray spectroscopyX-ray photoelectron spectroscopyComposite materialLayer (electronics)CoatingMagnesium Alloys: Properties and ApplicationsTitanium Alloys Microstructure and PropertiesNuclear Materials and Properties
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