Transcellular biosynthesis of leukotriene B4 orchestrates neutrophil swarming to fungi
Alex Hopke, Lin Tian, Allison K. Scherer, Ashley E. Shay, Kyle D. Timmer, Brittany Wilson-Mifsud, Michael K. Mansour, Charles N. Serhan, Daniel Irimia, Bryan P. Hurley
Abstract
for the purposes of orchestrating neutrophil swarming. These results further our understanding of how neutrophils coordinate their activities during swarming, which will be critical in the design of eventual therapies that can harness the power of swarming behavior.
Topics & Concepts
TranscellularBiosynthesisLeukotriene B4ChemistrySwarming (honey bee)MicrobiologyBiologyImmunologyBiochemistryInflammationEnzymeNeutrophil, Myeloperoxidase and Oxidative MechanismsS100 Proteins and Annexins