Flagellar Perturbations Activate Adhesion through Two Distinct Pathways in <i>Caulobacter crescentus</i>
David M. Hershey, Aretha Fiebig, Sean Crosson
Abstract
morphogenic program and those that are required for flagellar motility. Our results support a model in which a developmental and a mechanical signaling pathway operate in parallel downstream of the flagellum and converge to regulate adhesion. We conclude that the flagellum serves as a signaling hub by integrating internal and external cues to coordinate surface colonization and emphasize the role of signal integration in linking complex sets of environmental stimuli to individual behaviors.
Topics & Concepts
Caulobacter crescentusFlagellumCell biologyAdhesionBiologyChemistryBacterial proteinBacteriaGeneticsOrganic chemistryBacterial biofilms and quorum sensingPickering emulsions and particle stabilizationBiocrusts and Microbial Ecology