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Metal-Free Chemoselective <i>S</i>-Arylation of Sulfenamides To Access Sulfilimines

Xianda Wu, Yuqing Li, Minghong Chen, Fu‐Sheng He, Jie Wu

2023The Journal of Organic Chemistry55 citationsDOI

Abstract

-arylation of sulfenamides with diaryliodonium salts for the synthesis of sulfilimines is developed. The reaction proceeds smoothly under transition-metal-free and air conditions, giving rapid access to sulfilimines in good to excellent yields via selective S-C bond formation. This protocol is scalable and exhibits a broad substrate scope, good functional group tolerance, and excellent chemoselectivity.

Topics & Concepts

ChemoselectivityScope (computer science)Substrate (aquarium)ChemistryFunctional groupCombinatorial chemistryScalabilityComputer scienceCatalysisOrganic chemistryDatabaseProgramming languageOceanographyPolymerGeologySulfur-Based Synthesis TechniquesSynthesis and Catalytic ReactionsCatalytic C–H Functionalization Methods
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