Accurate long-read sequencing allows assembly of the duplicated RHD and RHCE genes harboring variants relevant to blood transfusion
Zhe Zhang, Hyun Hyung An, Sunitha Vege, Taishan Hu, Shiping Zhang, Timothy L. Mosbruger, Pushkala Jayaraman, Dimitri Monos, Connie M. Westhoff, Stella T. Chou
Topics & Concepts
GeneticsBiologyGenotypingStructural variationHaplotypeDNA sequencingGeneLocus (genetics)Computational biologyCopy-number variationGenomeAlleleGenotypeBlood groups and transfusionHemoglobinopathies and Related DisordersErythrocyte Function and Pathophysiology