Artificial intelligence method to design and fold alpha-helical structural proteins from the primary amino acid sequence
Zhao Qin, Lingfei Wu, Hui Sun, Siyu Huo, Tengfei Ma, Eugene J. Lim, Pin‐Yu Chen, Benedetto Marelli, Markus J. Buehler
Topics & Concepts
Protein designProtein structure predictionProtein secondary structureProtein foldingProtein structureFolding (DSP implementation)Rational designComputational biologyPeptide sequenceFold (higher-order function)Sequence (biology)Protein engineeringProtein sequencingAmino acidAb initioFunction (biology)Structural bioinformaticsComputer scienceBiologyEngineeringChemistryBiochemistryStructural engineeringGeneticsEnzymeGeneProgramming languageOrganic chemistryProtein Structure and DynamicsRNA and protein synthesis mechanismsSilk-based biomaterials and applications