METTL3-deficiency Suppresses Neural Apoptosis to Induce Protective Effects in Cerebral I/R Injury via Inhibiting RNA m6A Modifications: A Pre-clinical and Pilot Study
Gang Huang, Yuda Qiu, Yafei Fan, Jianfeng Liu
Topics & Concepts
Downregulation and upregulationAstrocyteApoptosisRNA methylationReperfusion injuryOxidative stressIschemiaBiologyMedicineCell biologyNeuroscienceInternal medicineMethylationMethyltransferaseCentral nervous systemBiochemistryGeneRNA modifications and cancerCancer-related molecular mechanisms researchCancer-related gene regulation