Sensitive determination of chlorpromazine in pharmaceutical formulations and biological fluids using solid phase extraction followed by HPLC-UV and spectrophotometric analysis
Raed F. Hassan, Jalal N. Jeber, Hussein Fares Abd‐Alrazack, Mohammad K. Hammood, M. Muhannad
Abstract
@CPTES nanoparticles enable rapid, reusable, and efficient extraction, reducing both analysis time and resource consumption. While tablet analysis validates method robustness, the primary application lies in trace CPZH detection in biological matrices. This green analytical approach offers a reliable, sensitive, and eco-friendly protocol for CPZH detection, highlighting its potential for broader applications in pharmaceutical and biomedical analysis.
Topics & Concepts
ChromatographyHigh-performance liquid chromatographySolid phase extractionChemistryExtraction (chemistry)Phase (matter)ChlorpromazinePharmacologyOrganic chemistryMedicineAnalytical Methods in PharmaceuticalsAnalytical Chemistry and SensorsAnalytical chemistry methods development