Photoinduced Decatungstate Anion-Catalyzed 1,4-Difunctionalization of 1,3-Butadienes via C–H Activation
Xiao‐Yun Ruan, Dan-Xing Wu, Wen‐Ao Li, Zihan Lin, Mostafa Sayed, Zhi‐Yong Han, Liu‐Zhu Gong
Abstract
This paper outlines an innovative three-component coupling strategy for the 1,4-difunctionalization of 1,3-butadiene, utilizing sodium decatungstate (NaDT) as a hydrogen atom transfer (HAT) photocatalyst. The photoinduced process efficiently generates homoallylic amino acid esters with 100% atom economy, employing readily available components under mild reaction conditions. This light-induced protocol eliminates the need for an additional transition metal catalysts, additives, or equivalent reducing agents. The study explored various C(sp 3 )–H bearing partners, butadienes, and α-iminoesters, demonstrating the versatility and synthetic utility of this method.