CSC01 shows promise as a potential inhibitor of the oncogenic G13D mutant of KRAS: an in silico approach
Olanrewaju Ayodeji Durojaye, Umer Ejaz, Henrietta Onyinye Uzoeto, Adeola Abraham Fadahunsi, Adebayo Oluwole Opabunmi, Daniel Emmanuel Ekpo, Divine Mensah Sedzro, Mukhtar Oluwaseun Idris
Topics & Concepts
KRASPharmacophoreMutantIn silicoComputational biologyVirtual screeningDocking (animal)Cancer researchBiologyChemistryMutationBioinformaticsGeneticsMedicineGeneNursingProtein Kinase Regulation and GTPase SignalingComputational Drug Discovery MethodsMelanoma and MAPK Pathways