Discovery of new Lenalidomide derivatives as potent and selective GSPT1 degraders
Yiying Wei, Xinxin Xu, Minchuan Jiang, Yongxing Wang, Yang Zhou, Zhen Wang, Zhang Zhang, Fengtao Zhou, Ke Ding, Ke Ding
Topics & Concepts
ChemistryU937 cellProteasomeApoptosisCell cycleCancer cellCancer researchBiochemistryCancerBiologyGeneticsProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysBiochemical and Molecular Research