Deuteration of terminal alkynes realizes simultaneous live cell Raman imaging of similar alkyne-tagged biomolecules
Syusuke Egoshi, Kosuke Dodo, Kenji Ohgane, Mikiko Sodeoka
Abstract
. Two-color Raman imaging of D-alkynes and H-alkynes made it possible to distinguish between and observe similar small molecules in live cells.
Topics & Concepts
BiomoleculeAlkyneRaman spectroscopyTerminal (telecommunication)Small moleculeLive cell imagingChemistryNanotechnologyCellMaterials scienceOpticsPhysicsBiochemistryComputer scienceTelecommunicationsCatalysisSpectroscopy Techniques in Biomedical and Chemical ResearchMass Spectrometry Techniques and ApplicationsAdvanced biosensing and bioanalysis techniques