Reduction in O-glycome induces differentially glycosylated CD44 to promote stemness and metastasis in pancreatic cancer
Frank Leon, Parthasarathy Seshacharyulu, Rama Krishna Nimmakayala, Seema Chugh, Saswati Karmakar, Palanisamy Nallasamy, Raghupathy Vengoji, Satyanarayana Rachagani, Jesse L. Cox, Kavita Mallya, Surinder K. Batra, Moorthy P. Ponnusamy
Topics & Concepts
Homeobox protein NANOGBiologyCancer stem cellCD44Cancer researchPancreatic cancerStem cellPopulationCancerImmunologyCell biologyInduced pluripotent stem cellBiochemistryIn vitroEmbryonic stem cellGeneticsMedicineEnvironmental healthGenePancreatic and Hepatic Oncology ResearchGlycosylation and Glycoproteins ResearchCancer Cells and Metastasis