Biomedical polymer scaffolds mimicking bone marrow niches to advance <i>in vitro</i> expansion of hematopoietic stem cells
Jing Hong, Wenlong Zheng, Xiaoqiong Wang, Ying Hao, Guosheng Cheng
Abstract
expansion of HSCs. Bone marrow transplantation and microenvironments are first introduced. Then, biomedical polymer scaffolds for the expansion of HSCs and future prospects are summarized and discussed.
Topics & Concepts
Stem cellHaematopoiesisBone marrowHematopoietic stem cellIn vitroHematopoietic stem cell transplantationBone Marrow Stem CellMaterials scienceCancer researchCell biologyBiomedical engineeringBiologyMedicineImmunologyBiochemistryMesenchymal stem cell research3D Printing in Biomedical ResearchHematopoietic Stem Cell Transplantation