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Design, synthesis, and evaluation of hydrazones as dual inhibitors of ryanodine receptors and acetylcholinesterases for Alzheimer’s disease

Fan Yang, Jiangang Zhao, Guang Chen, Hao Han, Shuang Hu, Ningwei Wang, Junqin Wang, Yuzhen Chen, Zihao Zhou, Baozhu Dai, Yunlei Hou, Yajing Liu

2023Bioorganic Chemistry14 citationsDOI

Topics & Concepts

ChemistryRyanodine receptorReceptorDual (grammatical number)PharmacologyAlzheimer's diseaseBiochemistryDiseaseInternal medicineLiteratureArtMedicineCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsNeuroscience and Neuropharmacology Research
Design, synthesis, and evaluation of hydrazones as dual inhibitors of ryanodine receptors and acetylcholinesterases for Alzheimer’s disease | Litcius