Out of the Dark, into the Light: Metabolic Fluorescent Labeling of Nucleic Acids
J. Iven H. Knaack, Chris Meier
Abstract
This review outlines recent advances in live-cell imaging techniques for nucleic acids. We describe the evolution of these methods, particularly highlighting the development of metabolic labeling approaches compatible with living systems using fluorescence-based labeling.
Topics & Concepts
Nucleic acidFluorescenceChemistryFluorescent labellingBiophysicsBiochemistryBiologyPhysicsQuantum mechanicsClick Chemistry and ApplicationsChemical Synthesis and AnalysisCancer Research and Treatments