CTLA-4 blockade induces tumor pyroptosis via CD8+ T cells in head and neck squamous cell carcinoma
Shuo Wang, Zhi‐Zhong Wu, Su‐Wen Zhu, Shu‐Cheng Wan, Mengjie Zhang, Boxin Zhang, Qi‐Chao Yang, Yao Xiao, Hao Li, Liang Mao, Zhiyong Wang, J. Silvio Gutkind, Zhi‐Jun Sun
Topics & Concepts
PyroptosisBlockadeHead and neck squamous-cell carcinomaBasal cellCytotoxic T cellCD8Cancer researchHead and neckMedicineBiologyInternal medicineImmunologyHead and neck cancerImmune systemInflammationCancerReceptorSurgeryIn vitroInflammasomeBiochemistryInflammasome and immune disordersCancer Immunotherapy and BiomarkersImmune Cell Function and Interaction