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Visible-light-driven cascade radical cyclization toward the synthesis of α-carbonyl alkyl-substituted benzimidazo[2,1-<i>a</i>]isoquinolin-6(5<i>H</i>)-one derivatives

Jing Liu, Hong‐Li Huang, Chen Wang, Yinghua Li, Huaqiang Li, Honggang Hu, Shipeng He, Hua Tang, Fei Gao

2021RSC Advances20 citationsDOIOpen Access PDF

Abstract

A visible-light-driven radical cyclization method has been developed for synthesis of α -carbonyl alkyl-substituted benzimidazo[2,1- a ]isoquinolin-6(5 H )-ones. This reaction is characterized by excellent yields and good functional group tolerance.

Topics & Concepts

AlkylChemistryCascadeMedicinal chemistryPhotochemistryOrganic chemistryChromatographyRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques
Visible-light-driven cascade radical cyclization toward the synthesis of α-carbonyl alkyl-substituted benzimidazo[2,1-<i>a</i>]isoquinolin-6(5<i>H</i>)-one derivatives | Litcius