Possible effects of titanium dioxide particles on human liver, intestinal tissue, spleen and kidney after oral exposure
Walter Brand, Ruud Peters, Hedwig Braakhuis, L Maslankiewicz, Agnes G. Oomen
Abstract
exposure cannot be excluded. Data for comparison with Ti levels in human intestinal tissue, spleen and kidney with effect concentrations were too limited to draw firm conclusions. The Ti levels, though, are similar or higher than those found in liver, suggesting these tissues may be relevant too.
Topics & Concepts
Adverse Outcome PathwayKidneySpleenAnimal studiesAdverse effectOxidative stressMedicineInflammationPhysiologyPathologyReactive oxygen speciesInternal medicineGastroenterologyBiologyBiochemistryComputational biologyNanoparticles: synthesis and applicationsHeavy Metal Exposure and ToxicityAnesthesia and Neurotoxicity Research