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A Review on the Recent Multicomponent Synthesis of 4H-Pyran Derivatives

Ghada G. El‐Bana, Mohamed A. Salem, Mohamed H. Helal, Osama Alharbi, Moustafa A. Gouda

2022Mini-Reviews in Organic Chemistry20 citationsDOI

Abstract

Abstract: 4H-Pyran is a well-known moiety, which appears in various natural and synthetic products. These compounds include various biological activities like anti-hepatotoxic, antitumor, anti-inflammatory, antioxidant, anti-spasmolytic, diuretic, estrogenic, anticoagulant, antifungal, antiviral, anti-helminthic, antimicrobial, hypothermal, anti-tubercular, anti-HIV, herbicidal, anticonvulsant and analgesic activity. This review has summarized an overview of general strategies that allow the design of 4H-pyran derivatives via catalyzed one-pot multicomponent reactions.

Topics & Concepts

PyranAntimicrobialAntifungalMoietyChemistryCombinatorial chemistryOrganic chemistryPharmacologyBiologyMicrobiologyMulticomponent Synthesis of HeterocyclesSynthesis of heterocyclic compoundsSynthesis of Organic Compounds
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