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Modulation of pharyngeal swallowing by bolus volume and viscosity

Lara Ferris, Sebastian Doeltgen, Charles Cock, Nathalie Rommel, Mistyka Schar, Sílvia Carrión, Ingrid Scholten, Taher Omari

2020American Journal of Physiology-Gastrointestinal and Liver Physiology48 citationsDOIOpen Access PDF

Abstract

The neuromodulation of the healthy oropharyngeal swallow response was described in relation to bolus volume and viscosity challenges, using intraluminal pressure and impedance topography methods. Among a wide range of physiological measures, those indicative of distension pressure, luminal opening, and flow timing were most significantly altered by bolus condition, and therefore can be considered to be potential markers of swallow neuromodulation. The study methods and associated findings inform a diagnostic framework for swallow assessment in patients with oropharyngeal dysphagia.

Topics & Concepts

Bolus (digestion)DysphagiaSwallowingDistensionMedicineOropharyngeal dysphagiaNeuromodulationAnesthesiaSurgeryInternal medicineStimulationDysphagia Assessment and ManagementVoice and Speech DisordersTracheal and airway disorders
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