Matrine alleviates oxidative stress and ferroptosis in severe acute pancreatitis-induced acute lung injury by activating the UCP2/SIRT3/PGC1α pathway
Hongzhong Jin, Kailiang Zhao, Juanjuan Li, Zhiliang Xu, Shichong Liao, Shengrong Sun
Topics & Concepts
MatrineOxidative stressSIRT3PharmacologyReactive oxygen speciesInflammationProinflammatory cytokineChemistryMedicineImmunologySirtuinBiochemistryChromatographyGeneAcetylationPancreatitis Pathology and TreatmentInflammasome and immune disordersHeme Oxygenase-1 and Carbon Monoxide