Zinc Catalyzed Hydroboration of Esters and Nitriles with Pinacolborane
Gobbilla Sai Kumar, Ravi Kumar, Abhijit Sau, Vadapalli Chandrasekhar, Tarun K. Panda
Abstract
We developed a bench-stable iminopyridine-ligated zinc complex for the effective catalytic hydroboration of esters and nitriles under solvent-free conditions. Various esters and nitriles bearing different functionalities were selectively reduced to form corresponding alcohols and amines in good yields. Detailed Hammett plots are provided to explain the electronic effects on the phenyl ring.
Topics & Concepts
HydroborationChemistryZincCatalysisOrganic chemistrySolventRing (chemistry)Organoboron and organosilicon chemistryAsymmetric Hydrogenation and CatalysisChemical Synthesis and Reactions