Deuterium Metabolic Imaging of Alzheimer Disease at 3-T Magnetic Field Strength: A Pilot Case-Control Study
Alixander S. Khan, Katie A. Peterson, Orsolya Vittay, Mary A. McLean, Joshua Kaggie, John T. O’Brien, James B. Rowe, Ferdia A. Gallagher, Tomasz Matys
Abstract
= .04), suggesting an impairment of oxidative glucose metabolism in AD. However, there was no evidence of localization of these changes to the expected regions of metabolic impairment at MRSI, presumably due to insufficient spatial resolution. Conclusion DMI at 3 T demonstrated impairment of oxidative glucose metabolism in the brains of patients with AD but no evidence of regional signal differences. © RSNA, 2024
Topics & Concepts
MedicineDiseaseDeuteriumField strengthAlzheimer's diseaseMagnetic resonance imagingNuclear magnetic resonanceMagnetic fieldInternal medicineRadiologyNuclear physicsPhysicsQuantum mechanicsAdvanced MRI Techniques and ApplicationsFunctional Brain Connectivity StudiesAdvanced NMR Techniques and Applications