MicroRNAs as a Potential Biomarker in the Diagnosis of Cardiovascular Diseases
Dagmar Kramná, Petra Riedlová, Vítězslav Jiřík
Abstract
Cardiovascular diseases (CVD) are the leading cause of death in most developed countries. MicroRNAs (miRNAs) are highly investigated molecules not only in CVD but also in other diseases. Several studies on miRNAs continue to reveal novel miRNAs that may play a role in CVD, in their pathogenesis in diagnosis or prognosis, but evidence for clinical implementation is still lacking. The aim of this study is to clarify the diagnostic potential of miRNAs in some CVDs.
Topics & Concepts
microRNABiomarkerDiagnostic biomarkerDiseasePathogenesisMedicineCause of deathBioinformaticsClinical diagnosisBiologyIntensive care medicinePathologyGeneGeneticsMicroRNA in disease regulationCircular RNAs in diseasesCancer-related molecular mechanisms research