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FcRn overexpression in human cancer drives albumin recycling and cell growth; a mechanistic basis for exploitation in targeted albumin-drug designs

Maja Thim Larsen, Ole Aalund Mandrup, Karen Kræmmer Schelde, Yonglun Luo, Karina D. Sørensen, Frederik Dagnæs‐Hansen, Jason Cameron, Magnus Stougaard, Torben Steiniche, Kenneth A. Howard

2020Journal of Controlled Release43 citationsDOI

Topics & Concepts

AlbuminDrugHuman albuminPharmacologyTargeted drug deliveryChemistryCell growthCancer researchMedicineBiochemistryMonoclonal and Polyclonal Antibodies ResearchGlycosylation and Glycoproteins ResearchChronic Lymphocytic Leukemia Research
FcRn overexpression in human cancer drives albumin recycling and cell growth; a mechanistic basis for exploitation in targeted albumin-drug designs | Litcius