DABCO as a practical catalyst for aromatic halogenation with <i>N</i>-halosuccinimides
Haiyan Xu, Lanping Hu, Guanghua Zhu, Yueping Zhu, Yang Wang, Zheng‐Guang Wu, You Zi, Weichun Huang
Abstract
A simple and practical synthetic approach for synthesis of aromatic halides is developed. Simple Lewis base, DABCO, is used as the catalyst. This arene halogenation process proceedes conveniently and efficiently at ambient conditions, providing the desired products in good to excellent yields and selectivity.
Topics & Concepts
DABCOHalogenationCatalysisChemistryOrganic chemistryMedicinal chemistryCatalytic C–H Functionalization MethodsOxidative Organic Chemistry ReactionsVanadium and Halogenation Chemistry