Fighting drug-resistant lung cancer by induction of NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated ferroptosis
Jie Yu, Bingling Zhong, Lin Zhao, Ying Hou, Nana Ai, Jin‐Jian Lu, Wei Ge, Xiuping Chen
Topics & Concepts
Lipid peroxidationNAD+ kinaseCancer cellCisplatinSmall interfering RNAReactive oxygen speciesA549 cellPharmacologyBiologyMolecular biologyDrug resistanceChemistryBiochemistryApoptosisCancerTransfectionOxidative stressEnzymeMicrobiologyGeneChemotherapyGeneticsFerroptosis and cancer prognosisRNA modifications and cancerGenomics, phytochemicals, and oxidative stress