Downregulation of SHMT2 promotes the prostate cancer proliferation and metastasis by inducing epithelial-mesenchymal transition
Lei Chen, Hailong Liu, Yiyi Ji, Zehua Ma, Kai Shen, Xun Shangguan, Hongyang Qian, Yu Zhao, Chun-Wu Pan, Wei Xue
Topics & Concepts
Prostate cancerEpithelial–mesenchymal transitionBiologyDownregulation and upregulationCancer researchSerine hydroxymethyltransferaseMetastasisCancerCell growthProstateSerineCell biologyGeneBiochemistryGeneticsPhosphorylationEpigenetics and DNA MethylationCancer-related gene regulationCancer, Hypoxia, and Metabolism