Role of Cytokines and Other Soluble Factors in Tumor Development: Rationale for New Therapeutic Strategies
Andrea Cavazzoni, Graziana Digiacomo
Abstract
Many cytokines control tumor development by directly lowering cancer cell proliferation and inducing apoptotic cell death, or indirectly by activating the antitumoral activity of specific immune cells such as NK or CD8+ T-lymphocytes [...]
Topics & Concepts
Immune systemApoptosisCD8Cancer researchProgrammed cell deathImmunologyCell growthCancerBiologyBiochemistryGeneticsImmune Cell Function and InteractionImmune cells in cancerCancer Immunotherapy and Biomarkers