A near-infrared light-activated nanoprobe for simultaneous detection of hydrogen polysulfide and sulfur dioxide in myocardial ischemia–reperfusion injury
Xianzhu Luo, Cuiling Zhang, Chenyang Yue, Yuelin Jiang, Fei Yang, Yuezhong Xian
Abstract
levels were up-regulated during I/R. The NIR light-activated dual-responsive nanoprobe could be a powerful tool for myocardial I/R injury diagnosis. Moreover, we also found that inhibiting the initiation of the ferroptosis process contributed to attenuating cardiac I/R injury, which indicated great potential for treating I/R injury.
Topics & Concepts
NanoprobeMyocardial ischemiaIschemiaReperfusion injuryPolysulfideMedicineChemistryBiophysicsInternal medicineMaterials scienceNanotechnologyBiologyElectrolyteNanoparticlePhysical chemistryElectrodeSulfur Compounds in BiologyRedox biology and oxidative stressEicosanoids and Hypertension Pharmacology