New benzenesulfonamide scaffold-based cytotoxic agents: Design, synthesis, cell viability, apoptotic activity and radioactive tracing studies
Yassin M. Nissan, Khaled O. Mohamed, Wafaa Ahmed, Dina M. Ibrahim, Marwa Sharaky, Tamer M. Sakr, M. A. Motaleb, Ahmed Maher, Reem K. Arafa
Topics & Concepts
ChemistryCytotoxicityApoptosisCell cycleCytotoxic T cellDoxorubicinViability assayCyclin-dependent kinase 1Cell cultureCell cycle checkpointPharmacologyBiodistributionIn vitroCancer researchBiochemistryInternal medicineBiologyChemotherapyMedicineGeneticsSynthesis and biological activityEnzyme function and inhibitionSynthesis and Characterization of Heterocyclic Compounds