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Immune response of COVID-19 vaccines in solid cancer patients: A meta-analysis

Tiantian Hua, Rui Fan, Fan Yang, Feng Chen

2024Human Vaccines & Immunotherapeutics13 citationsDOIOpen Access PDF

Abstract

= 4), respectively. Subgroup analysis finds that study sample size, timing of antibody testing, and vaccine type have influence on the results; Seroconversion rates after COVID-19 vaccination are significantly lower in patients with solid malignancies, especially after the first dose, then shrinking gradually after the following two vaccinations, indicating that subsequent doses or a booster dose should be considered for the effectiveness of this subpopulation.

Topics & Concepts

Immune systemCoronavirus disease 2019 (COVID-19)MedicineMeta-analysis2019-20 coronavirus outbreakCancerImmunologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyInternal medicineDiseaseInfectious disease (medical specialty)OutbreakCOVID-19 and healthcare impactsSARS-CoV-2 and COVID-19 ResearchCOVID-19 Impact on Reproduction