Development of antibody-aptamer sandwich-like immunosensor based on RCA and Nicked-PAM CRISPR/Cas12a system for the ultra-sensitive detection of a biomarker
Wen Wang, Lu Geng, Yiyang Zhang, Weili Shen, Bin Meng, Tingting Gong, Zhiyong Hu, Changjiang Guo, Tianhui Wang, Tieqiang Sun, Tieqiang Sun
Topics & Concepts
AptamerChemistryRolling circle replicationCRISPRDetection limitBiosensorLinear rangeChromatographyMolecular biologyDNABiochemistryPolymeraseGeneBiologyAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic EngineeringBiosensors and Analytical Detection