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Development of antibody-aptamer sandwich-like immunosensor based on RCA and Nicked-PAM CRISPR/Cas12a system for the ultra-sensitive detection of a biomarker

Wen Wang, Lu Geng, Yiyang Zhang, Weili Shen, Bin Meng, Tingting Gong, Zhiyong Hu, Changjiang Guo, Tianhui Wang, Tieqiang Sun, Tieqiang Sun

2023Analytica Chimica Acta13 citationsDOI

Topics & Concepts

AptamerChemistryRolling circle replicationCRISPRDetection limitBiosensorLinear rangeChromatographyMolecular biologyDNABiochemistryPolymeraseGeneBiologyAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic EngineeringBiosensors and Analytical Detection
Development of antibody-aptamer sandwich-like immunosensor based on RCA and Nicked-PAM CRISPR/Cas12a system for the ultra-sensitive detection of a biomarker | Litcius