Gliotoxin, an Immunosuppressive Fungal Metabolite, Primes Plant Immunity: Evidence from <i>Trichoderma virens</i> -Tomato Interaction
Rinat Zaid, Roni Koren, Efrat Kligun, Rupali Gupta, Meirav Leibman‐Markus, Prasun K. Mukherjee, Charles M. Kenerley, Maya Bar, Benjamin A. Horwitz
Abstract
A single fungal metabolite induces far-reaching transcriptomic reprogramming in the plant, priming immune responses and defense, in contrast to its immunosuppressive effect on animal cells. While the negative effects of gliotoxin-producing Trichoderma strains on growth may be observed only under a particular set of laboratory conditions, gliotoxin-linked molecular patterns, including the potential for limited cell death, could strongly prime plant defense, even in mature soil-grown plants in which the same Trichoderma strain promotes growth.
Topics & Concepts
GliotoxinBiologyTrichodermaMetaboliteSecondary metabolitePriming (agriculture)ReprogrammingImmune systemMicrobiologyBotanyImmunologyCellBiochemistryGeneAspergillus fumigatusGerminationPlant-Microbe Interactions and ImmunityPlant tissue culture and regenerationTransgenic Plants and Applications